Giardiasis, Drug Resistance, and New Target Discovery

Title: Giardiasis, Drug Resistance, and New Target Discovery

Volume: 10 Issue: 4

Author(s): Hai-Feng Tian, Bing Chen and Jian-Fan Wen

Affiliation:

Keywords: Giardia lamblia, giardiasis, drug resistance, vaccine, target

Abstract: Giardiasis is a worldwide parasitic disease caused by the protozoan Giardia lamblia in humans and other animals, especially live stocks. Here, we briefly review the current state of therapeutic availability for giardiasis, including chemical drugs and vaccines, and the dilemma in the prevention and treatment of this disease, including the emergence of drug resistance and the shortage of vaccine (especially for humans). Future efforts and progress in controlling giardiasis are expected in three aspects: clarification of the drug resistance mechanisms, development of efficient vaccines, and identification of more targets for new drugs and vaccines.

Cite this article as:

Tian Hai-Feng, Chen Bing and Wen Jian-Fan, Giardiasis, Drug Resistance, and New Target Discovery, Infectious Disorders - Drug Targets 2010; 10 (4) . https://dx.doi.org/10.2174/187152610791591629