Cyclodextrins: More than Pharmaceutical Excipients

Title: Cyclodextrins: More than Pharmaceutical Excipients

Volume: 10 Issue: 8

Author(s): F.J. Otero-Espinar, A. Luzardo-Alvarez and J. Blanco-Mendez

Affiliation:

Keywords: Cyclodextrins, protein refolding, Bacillus anthracis, Cryptosporidium spp., Human Immunodeficiency Virus, immunomodulation, Leishmania spp., Plasmodium spp.

Abstract: Cyclodextrins are pharmaceutical excipients used to enhance the solubility, stability, safety and bioavailability of drugs. Recent findings have shown them to display adjuvant activity in vaccine therapy and prophylactic and therapeutic activity in the treatment of several host-pathogen infections. This article focuses on their activity and mechanism of action.

Cite this article as:

Otero-Espinar F.J., Luzardo-Alvarez A. and Blanco-Mendez J., Cyclodextrins: More than Pharmaceutical Excipients, Mini-Reviews in Medicinal Chemistry 2010; 10 (8) . https://dx.doi.org/10.2174/138955710791572479