Activatable Molecular Probes for Cancer Imaging

Title: Activatable Molecular Probes for Cancer Imaging

Volume: 10 Issue: 11

Author(s): Seulki Lee, Jin Xie and Xiaoyuan Chen

Affiliation:

Keywords: molecular probes, cancer imaging, imaging sciences, bionanoconjugation chemistry, activatable imaging probes, Molecular imaging, imaging techniques

Abstract: The development of highly sensitive and specific molecular probes for cancer imaging still remains a daunting challenge. Recently, interdisciplinary research at the interface of imaging sciences and bionanoconjugation chemistry has generated novel activatable imaging probes that can provide high-resolution imaging with ultra-low background signals. Activatable imaging probes are designed to amplify output imaging signals in response to specific biomolecular recognition or environmental changes in real time. This review introduces and highlights the unique design strategies and applications of various activatable imaging probes in cancer imaging.

Cite this article as:

Lee Seulki, Xie Jin and Chen Xiaoyuan, Activatable Molecular Probes for Cancer Imaging, Current Topics in Medicinal Chemistry 2010; 10 (11) . https://dx.doi.org/10.2174/156802610791384270