Current Review of Small Molecule Ret Kinase Inhibitors

Title: Current Review of Small Molecule Ret Kinase Inhibitors

Volume: 10 Issue: 2

Author(s): W.J. Zuercher, B.J. Turunen and K.E. Lackey

Affiliation:

Keywords: Ret kinase, protein tyrosine kinase inhibitors, thyroid cancer

Abstract: Aberrant Ret kinase activity has been implicated in multiple carcinomas and disorders. Many strategies have been implemented to identify Ret kinase inhibitors. This review details current efforts to discover novel small molecule Ret kinase inhibitiors. Furthermore, we compile a comprehensive list of Ret kinase inhibitors and describe clinical results of advanced assets with Ret inhibitory activity.

Cite this article as:

Zuercher W.J., Turunen B.J. and Lackey K.E., Current Review of Small Molecule Ret Kinase Inhibitors, Mini-Reviews in Medicinal Chemistry 2010; 10 (2) . https://dx.doi.org/10.2174/138955710791185154