Hologram QSAR Studies of N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides Derivatives as Selective Peripheral Benzodiazepine Receptor Ligands

Title: Hologram QSAR Studies of N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides Derivatives as Selective Peripheral Benzodiazepine Receptor Ligands

Volume: 7 Issue: 2

Author(s): M. Ye

Affiliation:

Keywords: Peripheral benzodiazepine receptor, Hologram QSAR

Abstract: Peripheral benzodiazepine receptor (PBR) is an important target for the development of drugs to treat anxiety and sleep disorders. Hologram QSAR models were built for good statistical results. Contribution map analysis explains the individual atomic contributions to the overall activity. This HQSAR model should be useful for the further development of novel structurally related PBR ligands.

Cite this article as:

Ye M., Hologram QSAR Studies of N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides Derivatives as Selective Peripheral Benzodiazepine Receptor Ligands, Letters in Drug Design & Discovery 2010; 7 (2) . https://dx.doi.org/10.2174/157018010790225886

DOI https://dx.doi.org/10.2174/157018010790225886	Print ISSN 1570-1808
Publisher Name Bentham Science Publisher	Online ISSN 1875-628X