Abstract
Ion exchange resin catalyzed multicomponent Biginelli reaction is studied for the synthesis of 3,4- dihydropyrimidin-2-ones. Among the various solid acid catalysts Indion-130 was found to be most efficient, recyclable and environmentally benign heterogeneous catalyst regarding reaction time, yield and ease of work up procedure.
Keywords: Biginelli reaction, 3,4-dihydropyrimidin-2-ones, Ion exchange resin, heterogeneous catalyst, Indion-130
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