Abstract
A simple, efficient and green procedure has been developed for the synthesis of octahydroquinazolinone derivatives by Biginelli-type three-component cyclocondensation reactions of cyclic β-diketones, aldehydes and (thio)urea with p-TsOH catalysis in water.
Keywords: Octahydroquinazolinone, biginelli reaction, cyclic β-diketones, p-toluenesulfonic acid, synthesis, catalysis
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