Abstract
This short review describes the recently reported semi- and total syntheses of naturally occurring triterpenoid saponins. Accent is placed on natural monodesmosidic and bidesmosidic saponins of the oleanane- and lupane-type that possess potent pharmacological properties including cytotoxic and antitumor activities.
Keywords: Natural products, Saponins, Triterpenes, Chemical synthesis, Cytotoxic, Anticancer
Mini-Reviews in Organic Chemistry
Title: Recent Progress in the Synthesis of Naturally Occurring Triterpenoid Saponins
Volume: 6 Issue: 4
Author(s): Charles Gauthier, Jean Legault and Andre Pichette
Affiliation:
Keywords: Natural products, Saponins, Triterpenes, Chemical synthesis, Cytotoxic, Anticancer
Abstract: This short review describes the recently reported semi- and total syntheses of naturally occurring triterpenoid saponins. Accent is placed on natural monodesmosidic and bidesmosidic saponins of the oleanane- and lupane-type that possess potent pharmacological properties including cytotoxic and antitumor activities.
Export Options
About this article
Cite this article as:
Gauthier Charles, Legault Jean and Pichette Andre, Recent Progress in the Synthesis of Naturally Occurring Triterpenoid Saponins, Mini-Reviews in Organic Chemistry 2009; 6 (4) . https://dx.doi.org/10.2174/157019309789371541
DOI https://dx.doi.org/10.2174/157019309789371541 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Synthesis and Evaluation of Novel Erucin Analogues as Potential Antitumor Compounds
Letters in Organic Chemistry MicroRNA-21: From Cancer to Cardiovascular Disease
Current Drug Targets <i>In Silico</i> Anticancer Evaluation, Molecular Docking and Pharmacophore Modeling of Flavonoids against Various Cancer Targets
Letters in Drug Design & Discovery Editorial (Thematic Issue: The Lung and Winding Road: Twists and Turns on the Way to Personalized NSCLC Therapy)
Current Pharmaceutical Design Polymeric Micelles of Modified Chitosan Block Copolymer as Nanocarrier for Delivery of Paclitaxel
Current Nanomedicine Novel Inhibitors of Inosine Monophosphate Dehydrogenase in Patent Literature of the Last Decade
Recent Patents on Anti-Cancer Drug Discovery Graphical Abstracts:
Current Medical Imaging Diabetes and Vascular Disease: Basic Concepts of Nitric Oxide Physiology, Endothelial Dysfunction, Oxidative Stress and Therapeutic Possibilities
Current Vascular Pharmacology Strategies on the Development of Small Molecule Anticancer Drugs for Targeted Therapy
Mini-Reviews in Medicinal Chemistry Transcriptional Analysis of JAK/STAT Signaling in Glioblastoma Multiforme
Current Pharmacogenomics and Personalized Medicine Humoral Immunity in HIV-1 Exposure: Cause or Effect of HIV Resistance?
Current HIV Research Toxic Epidermal Necrolysis and Antifolate Drugs in Cancer Chemotherapy
Current Drug Safety Effects of Anticancer Drugs in Reproductive Parameters of Juvenile Male Animals and Role of Protective Agents
Anti-Cancer Agents in Medicinal Chemistry Studies on Anticancer Activities of Lactoferrin and Lactoferricin
Current Protein & Peptide Science Other Potential Therapeutic Targets in Thyroid Orbitopathy
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) A Review of Recent Advancements in Anti-tubercular Molecular Hybrids
Current Medicinal Chemistry Cyclooxygenase-2: Potential Role in Regulation of Drug Efflux and Multidrug Resistance Phenotype
Current Pharmaceutical Design Sulfonamides and Sulfonylated Derivatives as Anticancer Agents
Current Cancer Drug Targets Therapeutic Outlook of Pyrazole Analogs: A Mini Review
Mini-Reviews in Medicinal Chemistry Biochemical Mechanisms of Cisplatin Cytotoxicity
Anti-Cancer Agents in Medicinal Chemistry