Diastereoselective Addition of Organometallic Reagents to Diimines Derived from (R,R)-1,2-Diaminocyclohexane and Aromatic Aldehydes

Title: Diastereoselective Addition of Organometallic Reagents to Diimines Derived from (R,R)-1,2-Diaminocyclohexane and Aromatic Aldehydes

Volume: 6 Issue: 6

Author(s): Diego Savoia, Andrea Gualandi and Marco Bandini

Affiliation:

Keywords: Amine, 1,2-diaminocyclohexane, diastereoselectivity, imine, organometallic reagents

Abstract: The double addition of organolithium compounds and allylzinc bromide to the imines prepared from (R,R)-1,2- diaminocyclohexane by condensation with aromatic and heteroaromatic aldehydes gave secondary diamines with high yields and diastereoselectivities apart for the reaction of 2-pyridinealdehyde derivative which occurred with low to moderate stereocontrol.

Cite this article as:

Savoia Diego, Gualandi Andrea and Bandini Marco, Diastereoselective Addition of Organometallic Reagents to Diimines Derived from (R,R)-1,2-Diaminocyclohexane and Aromatic Aldehydes, Letters in Organic Chemistry 2009; 6 (6) . https://dx.doi.org/10.2174/157017809789124948