Antinociceptive Activity of Lectins from Diocleinae Seeds on Acetic Acid-Induced Writhing Test in Mice

Title: Antinociceptive Activity of Lectins from Diocleinae Seeds on Acetic Acid-Induced Writhing Test in Mice

Volume: 16 Issue: 9

Author(s): Fernanda R. Holanda, Andrelina N. Coelho-de-Sousa, Ana M.S. Assreuy, Jose Henrique Leal-Cardoso, Alana F. Pires, Kyria S. do Nascimento, Cicero S. Teixeira, Benildo S. Cavada and Claudia F. Santos

Affiliation:

Keywords: Lectins, Diocleinae subtribe, antinociception, Canavalia grandiflora, carbohydrate recognition

Abstract: Diocleinae lectins administered per oral route in mice inhibited the abdominal constrictions induced by acetic acid. The percentage of the lectins antinociception varied from 61% for Canavalia grandiflora (ConGf) to 20% for Dioclea violacea. ConGf inhibited contortions at all doses tested but not in a dose-dependent manner, involving carbohydrate recognition.

Cite this article as:

Holanda R. Fernanda, Coelho-de-Sousa N. Andrelina, Assreuy M.S. Ana, Leal-Cardoso Henrique Jose, Pires F. Alana, do Nascimento S. Kyria, Teixeira S. Cicero, Cavada S. Benildo and Santos F. Claudia, Antinociceptive Activity of Lectins from Diocleinae Seeds on Acetic Acid-Induced Writhing Test in Mice, Protein & Peptide Letters 2009; 16 (9) . https://dx.doi.org/10.2174/092986609789055304