Regulation of Endochondral Ossification by Osteogenic Growth Peptide CTerminal Pentapeptide [OGP(10-14)]

Title: Regulation of Endochondral Ossification by Osteogenic Growth Peptide CTerminal Pentapeptide [OGP(10-14)]

Volume: 16 Issue: 9

Author(s): Zhixin Chen, Min Chang, Yali Peng, Li Zhao, Yurui Zhan, Lijing Wang and Rui Wang

Affiliation:

Keywords: OGP(10-14), Regulation, Endochondral ossification

Abstract: In neonatal rat metatarsal organ culture, a bell-shaped dose-related curve in length of mineralized area, increases in the height of proliferative and hypertrophic zones, in the number of hypertrophic chondrocyte and in the amount of Runx2 mRNA, were revealed after treatment with OGP(10-14). We conclude that OGP(10-14) accelerates bone growth.

Cite this article as:

Chen Zhixin, Chang Min, Peng Yali, Zhao Li, Zhan Yurui, Wang Lijing and Wang Rui, Regulation of Endochondral Ossification by Osteogenic Growth Peptide CTerminal Pentapeptide [OGP(10-14)], Protein & Peptide Letters 2009; 16 (9) . https://dx.doi.org/10.2174/092986609789055395