Pharmacological and Lifestyle Factors Modulating Serum Paraoxonase-1 Activity

Title: Pharmacological and Lifestyle Factors Modulating Serum Paraoxonase-1 Activity

Volume: 9 Issue: 8

Author(s): Jordi Camps, Judit Marsillach and Jorge Joven

Affiliation:

Keywords: Apolipoprotein A-I, fibrates, high-density lipoproteins, lipid peroxidation, nutrition, paraoxonase-1, rosiglitazone, statins

Abstract: Paraoxonase-1 is a lactonase and an esterase and it plays a protective role in toxicity as well as in diseases involving oxidative stress. Recently, insights into how it may be modulated by environmental factors have acquired clinical relevance. This article reviews the state-of-the-art evidence regarding PON1 modulation by pharmacological products as well as nutritional and lifestyle factors.

Cite this article as:

Camps Jordi, Marsillach Judit and Joven Jorge, Pharmacological and Lifestyle Factors Modulating Serum Paraoxonase-1 Activity, Mini-Reviews in Medicinal Chemistry 2009; 9 (8) . https://dx.doi.org/10.2174/138955709788681591