Abstract
Ceric ammonium nitrate (CAN) catalyzed the one-pot synthesis of 2,2,4-trimethyl-1,2-dihydroquinoline derivatives from substituted anilines and acetone via a modified Skraup reaction. The methodology was used to synthesize a novel dihydroquinoline-based compound derived from an anti-inflammatory agent nimesulide.
Keywords: CAN, catalysis, aniline, dihydroquinoline
Letters in Organic Chemistry
Title: Ceric Ammonium Nitrate: An Efficient Catalyst for One-Pot Synthesis of 2,2,4-Trimethyl-1,2-dihydroquinolines
Volume: 7 Issue: 4
Author(s): Shylaprasad Durgadas, Vijay K. Chatare, Khagga Mukkanti and Sarbani Pal
Affiliation:
Keywords: CAN, catalysis, aniline, dihydroquinoline
Abstract: Ceric ammonium nitrate (CAN) catalyzed the one-pot synthesis of 2,2,4-trimethyl-1,2-dihydroquinoline derivatives from substituted anilines and acetone via a modified Skraup reaction. The methodology was used to synthesize a novel dihydroquinoline-based compound derived from an anti-inflammatory agent nimesulide.
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Cite this article as:
Durgadas Shylaprasad, K. Chatare Vijay, Mukkanti Khagga and Pal Sarbani, Ceric Ammonium Nitrate: An Efficient Catalyst for One-Pot Synthesis of 2,2,4-Trimethyl-1,2-dihydroquinolines, Letters in Organic Chemistry 2010; 7 (4) . https://dx.doi.org/10.2174/157017810791130586
DOI https://dx.doi.org/10.2174/157017810791130586 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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