C2-Symmetric Pyrrolidines Derived from Tartaric Acids: Versatile Chiral Building Blocks for Total Synthesis, Catalyst Design, Supramolecular and Medicinal Chemistry

Title: C2-Symmetric Pyrrolidines Derived from Tartaric Acids: Versatile Chiral Building Blocks for Total Synthesis, Catalyst Design, Supramolecular and Medicinal Chemistry

Volume: 6 Issue: 1

Author(s): Andreas Blum and Wibke E. Diederich

Affiliation:

Keywords: Tartaric Acids, C2-Symmetric Pyrrolidines, Chiral, Total Synthesis, Catalyst Design, Medicinal Chemistry

Abstract: Chiral 3,4-difunctionalized pyrrolidines, which can be derived from L-(+)- and D-(-)-tartaric acids, are useful and versatile building blocks in total synthesis, catalyst preparation as well as supramolecular and medicinal chemistry. The preparation of these azacycles, possible transformations and their application are described herein.

Cite this article as:

Blum Andreas and Diederich E. Wibke, C2-Symmetric Pyrrolidines Derived from Tartaric Acids: Versatile Chiral Building Blocks for Total Synthesis, Catalyst Design, Supramolecular and Medicinal Chemistry, Current Organic Synthesis 2009; 6 (1) . https://dx.doi.org/10.2174/157017909787314902