Synthetic Approaches to the 2007 New Drugs

Kevin   K.-C.   Liu; Subas   M.   Sakya; Christopher   J.   O'Donnell; Jin      Li

doi:10.2174/138955708786786435

Abstract

New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. These new chemical entities (NCEs) provide insights into molecular recognition and also serve as leads for designing future new drugs. This review covers the syntheses of 19 NCEs marketed in 2007.

Keywords: Synthesis, new drug, new chemical entities, medicine, therapeutic agents

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Mini-Reviews in Medicinal Chemistry

Title: Synthetic Approaches to the 2007 New Drugs

Volume: 8 Issue: 14

Author(s): Kevin K.-C. Liu, Subas M. Sakya, Christopher J. O'Donnell and Jin Li

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Keywords: Synthesis, new drug, new chemical entities, medicine, therapeutic agents

Abstract: New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. These new chemical entities (NCEs) provide insights into molecular recognition and also serve as leads for designing future new drugs. This review covers the syntheses of 19 NCEs marketed in 2007.

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Liu K.-C. Kevin, Sakya M. Subas, O'Donnell J. Christopher and Li Jin, Synthetic Approaches to the 2007 New Drugs, Mini-Reviews in Medicinal Chemistry 2008; 8 (14) . https://dx.doi.org/10.2174/138955708786786435