Highly Selective Catalytic Friedel – Crafts Acylation of Activated Aromatic Compounds Using the I2.DMF Complex as Catalyst

Title: Highly Selective Catalytic Friedel – Crafts Acylation of Activated Aromatic Compounds Using the I2.DMF Complex as Catalyst

Volume: 5 Issue: 8

Author(s): Faouzi Guenadil, Hocine Aichaoui, Didier M. Lambert, Christopher R. McCurdy and Jacques H. Poupaert

Affiliation:

Keywords: I2-DMF, AlCI3-DMF, anisole, aromatic substrates, heteroaromatic substrates, Friedel-Crafts reaction

Abstract: A novel method has been developped for synthesizing aryl ketones by means of I2-DMF mediated Friedel – Crafts acylation of aromatic substrates. The reaction is applicable to activated aromatic compounds. The present process is carried out under conditions involving minimal wastes and energy-consumption as compared to the use of molecular iodine.

Cite this article as:

Guenadil Faouzi, Aichaoui Hocine, Lambert M. Didier, McCurdy R. Christopher and Poupaert H. Jacques, Highly Selective Catalytic Friedel – Crafts Acylation of Activated Aromatic Compounds Using the I2.DMF Complex as Catalyst, Letters in Organic Chemistry 2008; 5 (8) . https://dx.doi.org/10.2174/157017808786857624