Facile and Efficient Synthesis of Ethyl 3-Oxo-5-arylthiopentanoates, the Precursors for Nazarov Reagent

H.   Surya   Prakash Rao; Shaik      Rafi; K.      Padmavathy

doi:10.2174/157017808785982121

Abstract

A facile, efficient and high-yielding two-step synthesis of 3-oxo-5-arylthiopentanoates - the precursors for Nazarov reagent - from low-cost bench top chemicals like thiophenols, acrylonitrile, zinc and ethyl bromoacetate via the Blaise reaction, is reported.

Keywords: Nazarov reagent, Blaise reaction, β-Keto ester

« Previous Next »

Rights & Permissions Print Cite

Letters in Organic Chemistry

Title: Facile and Efficient Synthesis of Ethyl 3-Oxo-5-arylthiopentanoates, the Precursors for Nazarov Reagent

Volume: 5 Issue: 7

Author(s): H. Surya Prakash Rao, Shaik Rafi and K. Padmavathy

Affiliation:

Keywords: Nazarov reagent, Blaise reaction, β-Keto ester

Abstract: A facile, efficient and high-yielding two-step synthesis of 3-oxo-5-arylthiopentanoates - the precursors for Nazarov reagent - from low-cost bench top chemicals like thiophenols, acrylonitrile, zinc and ethyl bromoacetate via the Blaise reaction, is reported.

Export Options

Export File:

RIS (for EndNote, Reference Manager, ProCite)

BibTeX

Text

Content:

Citation Only

Citation and Abstract

About this article

Cite this article as:

Prakash Rao Surya H., Rafi Shaik and Padmavathy K., Facile and Efficient Synthesis of Ethyl 3-Oxo-5-arylthiopentanoates, the Precursors for Nazarov Reagent, Letters in Organic Chemistry 2008; 5 (7) . https://dx.doi.org/10.2174/157017808785982121