Discovery of New Therapeutic Targets by the Informational Spectrum Method

Title: Discovery of New Therapeutic Targets by the Informational Spectrum Method

Volume: 9 Issue: 5

Author(s): Nevena Veljkovic, Sanja Glisic, Jelena Prljic, Vladimir Perovic, Maurizio Botta and Veljko Veljkovic

Affiliation:

Keywords: Bioinformatics, target, electron-ion interaction potential, informational spectrum method, H5N1, HIV-1, anthrax

Abstract: The field of bioinformatics has become a major part of the drug discovery pipeline playing a key role in improvement and acceleration of this time and money consuming process. Here we review the application of the informational spectrum method (ISM), a virtual spectroscopy method for structure/function analysis of proteins, in identification of functional protein domains representing candidate therapeutic targets for drugs against human immunodeficiency virus (HIV)-1, anthrax, highly pathogenic influenza virus H5N1 and cardiovascular diseases.

Cite this article as:

Veljkovic Nevena, Glisic Sanja, Prljic Jelena, Perovic Vladimir, Botta Maurizio and Veljkovic Veljko, Discovery of New Therapeutic Targets by the Informational Spectrum Method, Current Protein & Peptide Science 2008; 9 (5) . https://dx.doi.org/10.2174/138920308785915245