Hypothyroidism and High Plasma and Urine Iodine Levels Related to the Use of Gastrografin

Title: Hypothyroidism and High Plasma and Urine Iodine Levels Related to the Use of Gastrografin

Volume: 4 Issue: 3

Author(s): Susana Segura Ares, Miguel Saenz de Pipaon Marcos, Ana Isabel Ruiz-Diaz, Gabriela Morreale de Escobar and Jose Jimenez Quero

Affiliation:

Keywords: Thyroid hormones, TSH, thyroxine, newborn, iodinated contrast media

Abstract: We report the effect of Gastrografin on thyroid function in 7 neonates. Levels of free thyroxine and thyroid stimulating hormone, serum and urine iodine concentrations were determined before and after using gastrografin. Transient hypothyroidism was seen in 3 patients. No thyroid gland dysfunction was detected in the Neonatal Screening Program for congenital hypothyroidism before the administration of Gastrografin and thyroid antibodies were negative. Urine and serum iodine concentrations were elevated after Gastrografin administration. Normal thyroid hormone concentrations were observed in the other four infants. We suggest careful evaluation of thyroid function whenever Gastrografin is used.

Cite this article as:

Ares Segura Susana, de Pipaon Marcos Saenz Miguel, Ruiz-Diaz Isabel Ana, de Escobar Morreale Gabriela and Quero Jimenez Jose, Hypothyroidism and High Plasma and Urine Iodine Levels Related to the Use of Gastrografin, Current Pediatric Reviews 2008; 4 (3) . https://dx.doi.org/10.2174/157339608785855992