Abstract
The cerium (III), lanthanum (III) and neodymium (III) complexes of 5-aminoorotic acid were synthesized and their structures were determined by means of theoretical study, spectral and physicochemical analysis. Significant differences in the spectra of the complexes were observed as compared to the spectra of the ligand. The ligand and the complexes were tested for the antioxidant activity. The results obtained indicate that the tested compounds exerted a considerable antioxidant effect upon the evaluated radicals formation in the blood plasma of Wistar rat.
Keywords: Lanthanide (III) complexes, 5-Aminoorotic acid, antioxidant activity
Medicinal Chemistry
Title: New Lanthanide Complexes with Antioxidant Activity
Volume: 4 Issue: 4
Author(s): Irena Kostova, Maria Traykova and Vinod K. Rastogi
Affiliation:
Keywords: Lanthanide (III) complexes, 5-Aminoorotic acid, antioxidant activity
Abstract: The cerium (III), lanthanum (III) and neodymium (III) complexes of 5-aminoorotic acid were synthesized and their structures were determined by means of theoretical study, spectral and physicochemical analysis. Significant differences in the spectra of the complexes were observed as compared to the spectra of the ligand. The ligand and the complexes were tested for the antioxidant activity. The results obtained indicate that the tested compounds exerted a considerable antioxidant effect upon the evaluated radicals formation in the blood plasma of Wistar rat.
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Cite this article as:
Kostova Irena, Traykova Maria and Rastogi K. Vinod, New Lanthanide Complexes with Antioxidant Activity, Medicinal Chemistry 2008; 4 (4) . https://dx.doi.org/10.2174/157340608784872181
DOI https://dx.doi.org/10.2174/157340608784872181 |
Print ISSN 1573-4064 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6638 |
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