Ultrasound Assisted Selective Reduction of Chalcones to Dihydrochalcones by Zn/HOAc

Liang      Zhang; Weige      Zhang; Xin      Wang; Kai      Bao; Guodong      Lu; Jinshun      Lin

doi:10.2174/157017808784872025

Abstract

An efficient ultrasound assisted method has been developed for the chemoselective synthesis of dihydrochalcones from chalcones using Zn/HOAc as a reductive system. Under the reaction conditions, isolated double bonds, benzyloxy groups and aromatic halides are found to remain unaffected.

Keywords: Chemoselective reduction, dihydrochalcones, chalcones, ultrasound, Zn/HOAc

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Letters in Organic Chemistry

Title: Ultrasound Assisted Selective Reduction of Chalcones to Dihydrochalcones by Zn/HOAc

Volume: 5 Issue: 5

Author(s): Liang Zhang, Weige Zhang, Xin Wang, Kai Bao, Guodong Lu and Jinshun Lin

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Keywords: Chemoselective reduction, dihydrochalcones, chalcones, ultrasound, Zn/HOAc

Abstract: An efficient ultrasound assisted method has been developed for the chemoselective synthesis of dihydrochalcones from chalcones using Zn/HOAc as a reductive system. Under the reaction conditions, isolated double bonds, benzyloxy groups and aromatic halides are found to remain unaffected.

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Zhang Liang, Zhang Weige, Wang Xin, Bao Kai, Lu Guodong and Lin Jinshun, Ultrasound Assisted Selective Reduction of Chalcones to Dihydrochalcones by Zn/HOAc, Letters in Organic Chemistry 2008; 5 (5) . https://dx.doi.org/10.2174/157017808784872025