Antipsychotic Drugs and Cerebrovascular Events in Elderly Patients with Dementia: A Systematic Review

Title: Antipsychotic Drugs and Cerebrovascular Events in Elderly Patients with Dementia: A Systematic Review

Volume: 8 Issue: 8

Author(s): Sara Mazzucco, Andrea Cipriani, Corrado Barbui and Salvatore Monaco

Affiliation:

Keywords: Neuroleptics, typical antipsychotics, atypical antipsychotics, dopamine, dementia, cerebrovascular events

Abstract: Recently, Canadian, US and European health regulatory agencies issued warnings about an increased risk of stroke and death in elderly patients with dementia receiving atypical antipsychotics. Assessing both randomised and nonrandomised evidence, this systematic review found conflicting findings, particularly for risperidone. More research is needed to better inform clinical practice.

Cite this article as:

Mazzucco Sara, Cipriani Andrea, Barbui Corrado and Monaco Salvatore, Antipsychotic Drugs and Cerebrovascular Events in Elderly Patients with Dementia: A Systematic Review, Mini-Reviews in Medicinal Chemistry 2008; 8 (8) . https://dx.doi.org/10.2174/138955708784912175