Analysis of Protein Surface Patterns by Pocket Similarity Network

Zhi-Ping      Liu; Ling-Yun      Wu; Yong      Wang; Xiang-Sun      Zhang; Luonan      Chen

doi:10.2174/092986608784567474

Abstract

In this work, in order to reveal protein surface patterns in a systems biology framework, we analyze the similarity among the surface cavities by investigating the features of the pocket similarity network such as the community structure, the small-world property, the scale-free characteristic, and the hubs.

Keywords: Protein surface pattern, pocket similarity, complex network, functional genomics, systems biology

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Protein & Peptide Letters

Title: Analysis of Protein Surface Patterns by Pocket Similarity Network

Volume: 15 Issue: 5

Author(s): Zhi-Ping Liu, Ling-Yun Wu, Yong Wang, Xiang-Sun Zhang and Luonan Chen

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Keywords: Protein surface pattern, pocket similarity, complex network, functional genomics, systems biology

Abstract: In this work, in order to reveal protein surface patterns in a systems biology framework, we analyze the similarity among the surface cavities by investigating the features of the pocket similarity network such as the community structure, the small-world property, the scale-free characteristic, and the hubs.

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Liu Zhi-Ping, Wu Ling-Yun, Wang Yong, Zhang Xiang-Sun and Chen Luonan, Analysis of Protein Surface Patterns by Pocket Similarity Network, Protein & Peptide Letters 2008; 15 (5) . https://dx.doi.org/10.2174/092986608784567474