Host Defense Peptides and the New Line of Defence Against Multiresistant Infections

Title: Host Defense Peptides and the New Line of Defence Against Multiresistant Infections

Volume: 15 Issue: 3

Author(s): Lars Steinstraesser, Tobias Hirsch, Frank Jacobsen and Hans-Ulrich Steinau

Affiliation:

Keywords: Host defense peptides, bacterial infection, innate immune system, defensins, cathelicidins, munomodulation, anitbacterial activity

Abstract: Increasing antibiotic resistance has led to an urgent need for new therapeutic approaches. Host defense peptides are known to be antimicrobial and have revealed broad immunomodulatory functions for both innate and adaptive immunity. This review will focus on the role of host defense peptides in infection and immune response and discuss its potential and limitations as a future therapeutical agent.

Cite this article as:

Steinstraesser Lars, Hirsch Tobias, Jacobsen Frank and Steinau Hans-Ulrich, Host Defense Peptides and the New Line of Defence Against Multiresistant Infections, Protein & Peptide Letters 2008; 15 (3) . https://dx.doi.org/10.2174/092986608783744252