Autoimmunity and Celiac Disease

Title: Autoimmunity and Celiac Disease

Volume: 8 Issue: 2

Author(s): Antonio La Cava, Carmen Gianfrani and Riccardo Troncone

Affiliation:

Keywords: epidermal growth factor, glutenins, anti-endomysium antibodies, tissue transglutaminase type II, prolyl endopeptidases

Abstract: In celiac disease (CD), abnormal immune-mediated responses follow ingestion of gluten. Although the triggering agent is a dietary protein, the disease has autoimmune components because of the presence of autoantibodies and its association with autoimmune conditions. We review the most recent studies on CD pathogenesis and the possibilities to modulate immune dysfunction in CD.

Cite this article as:

Cava La Antonio, Gianfrani Carmen and Troncone Riccardo, Autoimmunity and Celiac Disease, Mini-Reviews in Medicinal Chemistry 2008; 8 (2) . https://dx.doi.org/10.2174/138955708783498113