Technological Advances in Antigen Delivery and Synthetic Peptide Vaccine Developmental Strategies

Title: Technological Advances in Antigen Delivery and Synthetic Peptide Vaccine Developmental Strategies

Volume: 1 Issue: 4

Author(s): C. Olive, I. Toth and D. Jackson

Affiliation:

Keywords: receptor (TCR), antigen presenting cells (APC), immunogens, B-cell epitopes

Abstract: Significant advances have been made in the field of peptide chemistry, especially in the design of synthetic peptide immunogens which has led to new concepts and strategies for human vaccine development. This article reviews some of these technological advances and approaches to vaccine design including the multiple antigenic peptide system, the lipid polylysine core peptide system, the polymerization of peptides into multivalent immunogens and self adjuvanting synthetic peptide-based immunogens.

Cite this article as:

Olive C., Toth I. and Jackson D., Technological Advances in Antigen Delivery and Synthetic Peptide Vaccine Developmental Strategies, Mini-Reviews in Medicinal Chemistry 2001; 1 (4) . https://dx.doi.org/10.2174/1389557013406666