Abstract
The peptide Boc-(Gly-Dpg-Gly)3-OBzl (I) has been synthesized to examine the conformational preferences of Dpg residues in a peptide sequence rich in glycine, which is known to be a poor helix promoter. The detailed NMR studies revealed that peptide (I) adopts a helical conformation in CDCl3.
Keywords: Propyl Glycine, Glycine Rich Peptide
Protein & Peptide Letters
Title: Conformation of Di-N-Propyl Glycine Residue in a Glycine Rich Peptide Sequence
Volume: 8 Issue: 4
Author(s): Kalpana Bhargava and R. Balaji Rao
Affiliation:
Keywords: Propyl Glycine, Glycine Rich Peptide
Abstract: The peptide Boc-(Gly-Dpg-Gly)3-OBzl (I) has been synthesized to examine the conformational preferences of Dpg residues in a peptide sequence rich in glycine, which is known to be a poor helix promoter. The detailed NMR studies revealed that peptide (I) adopts a helical conformation in CDCl3.
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Cite this article as:
Bhargava Kalpana and Rao Balaji R., Conformation of Di-N-Propyl Glycine Residue in a Glycine Rich Peptide Sequence, Protein & Peptide Letters 2001; 8 (4) . https://dx.doi.org/10.2174/0929866013409346
DOI https://dx.doi.org/10.2174/0929866013409346 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
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