Biological Properties and Therapeutic Potential of Bilirubin

Title: Biological Properties and Therapeutic Potential of Bilirubin

Volume: 3 Issue: 3

Author(s): Ross P. McGeary, Alexander J. Szyczew and Istvan Toth

Affiliation:

Keywords: Bilirubin, jaundice, antioxidant

Abstract: Bilirubin was long considered a useless metabolite of heme catabolism, responsible for the clinical manifestation of jaundice, and potentially toxic in high doses, particularly in neonates. In the past two decades the potent biological properties of bilirubin, particularly as an antioxidant, have been recognised, and this has prompted a number of investigations into this molecule concerning its in vitro and in vivo properties. This review summarises that work, as well as more recent investigations into the potential therapeutic uses of bilirubin.

Cite this article as:

McGeary P. Ross, Szyczew J. Alexander and Toth Istvan, Biological Properties and Therapeutic Potential of Bilirubin, Mini-Reviews in Medicinal Chemistry 2003; 3 (3) . https://dx.doi.org/10.2174/1389557033488213