Direct Observation of Structure Transition of Donor-Acceptor Labeled Peptides: Temperature Dependence of Fluorescence Quenching Kinetics

Title: Direct Observation of Structure Transition of Donor-Acceptor Labeled Peptides: Temperature Dependence of Fluorescence Quenching Kinetics

Volume: 10 Issue: 1

Author(s): Wei Min and Lin Sun

Affiliation:

Keywords: electron transfer, fluorescence quenching, peptides, structure transition, molecular switches, labeled peptides

Abstract: From the temperature dependence of fluorescence quenching kinetics, a novel temperaturesensitive structure transition was discovered in a donor-acceptor labeled peptides. Perfect agreement of related abrupt changes in a1,t1 andt2 gives strong support for the existence of this structure transition, which suggests it is possible to develop peptides that can be rapidly and reversibly switched between two structure states in response to temperature shift.

Cite this article as:

Min Wei and Sun Lin, Direct Observation of Structure Transition of Donor-Acceptor Labeled Peptides: Temperature Dependence of Fluorescence Quenching Kinetics, Protein & Peptide Letters 2003; 10 (1) . https://dx.doi.org/10.2174/0929866033408255