7-Keto-Δ5-Steroids: Key-Molecules Owning Particular Biological and Chemical Interest

Title: 7-Keto-Δ5-Steroids: Key-Molecules Owning Particular Biological and Chemical Interest

Volume: 3 Issue: 6

Author(s): E. S. Arsenou, M. A. Fousteris, A. I. Koutsourea and S. S. Nikolaropoulos

Affiliation:

Keywords: 7-keto-, allylic oxidation, 7-keto-cholesterol, 7-keto-dhea, anticancer activity, aromatase inhibitors, apoptosis

Abstract: 7-keto-Δ5-steroids have been suggested for the treatment of several diseases. Their significant biological profile resulted in the development of a great number of methods and reagents for the allylic oxidation of Δ5-steroids. These methods and the biological evaluation of the main oxidized Δ5-steroids are summarized.

Cite this article as:

Arsenou S. E., Fousteris A. M., Koutsourea I. A. and Nikolaropoulos S. S., 7-Keto-Δ5-Steroids: Key-Molecules Owning Particular Biological and Chemical Interest, Mini-Reviews in Medicinal Chemistry 2003; 3 (6) . https://dx.doi.org/10.2174/1389557033487953