Synthetic Approaches to the 2002 New Drugs

Jin      Li; Kevin   K.-C.   Liu

doi:10.2174/1389557043487457

Abstract

New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. In addition, these new chemical entities (NCEs) not only provide insights into molecular recognition, but also serve as drug-like leads for designing future new drugs. Therefore, it is important to be acquainted with these new structures as well as their syntheses. To these ends, this review covers the syntheses of 28 NCEs marketed in 2002.

Keywords: synthesis, New drug, new chemical entities, medicine, therapeutic agents

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Mini-Reviews in Medicinal Chemistry

Title: Synthetic Approaches to the 2002 New Drugs

Volume: 4 Issue: 2

Author(s): Jin Li and Kevin K.-C. Liu

Affiliation:

Keywords: synthesis, New drug, new chemical entities, medicine, therapeutic agents

Abstract: New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. In addition, these new chemical entities (NCEs) not only provide insights into molecular recognition, but also serve as drug-like leads for designing future new drugs. Therefore, it is important to be acquainted with these new structures as well as their syntheses. To these ends, this review covers the syntheses of 28 NCEs marketed in 2002.

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Li Jin and Liu K.-C. Kevin, Synthetic Approaches to the 2002 New Drugs, Mini-Reviews in Medicinal Chemistry 2004; 4 (2) . https://dx.doi.org/10.2174/1389557043487457