Further Advances in the Synthesis of α,β-Difunctionalised Pyrroles

Severine      Hebbe; Luc      Dechoux

doi:10.2174/1570178043401027

Abstract

The reactivity of pyrrololactone 3 towards reductive and alkylating agents has been studied and the synthesis of diverse α, β-difunctionalised pyrroles is presented. The ambivalent reactivity of compound 3 towards the different nucleophilic reagents has been rationalised.

Keywords: pyrrole, lactone, lactol, iminium, phenylglycinol

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Letters in Organic Chemistry

Title: Further Advances in the Synthesis of α,β-Difunctionalised Pyrroles

Volume: 1 Issue: 3

Author(s): Severine Hebbe and Luc Dechoux

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Keywords: pyrrole, lactone, lactol, iminium, phenylglycinol

Abstract: The reactivity of pyrrololactone 3 towards reductive and alkylating agents has been studied and the synthesis of diverse α, β-difunctionalised pyrroles is presented. The ambivalent reactivity of compound 3 towards the different nucleophilic reagents has been rationalised.

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Hebbe Severine and Dechoux Luc, Further Advances in the Synthesis of α,β-Difunctionalised Pyrroles, Letters in Organic Chemistry 2004; 1 (3) . https://dx.doi.org/10.2174/1570178043401027