Abstract
Solid-phase methods for the preparation of hydantoins are reviewed. Furthermore, an optimized method based on the concourse of 1,1-carbonyldiimidazole allows the preparation of hydantoins without loss of chiral integrity.
Keywords: amino acid, combinatorial chemistry, cyclization, libraries, solid support
Letters in Organic Chemistry
Title: Re-Evaluation of a Solid-Phase Hydantoin Synthesis
Volume: 1 Issue: 3
Author(s): Jesus Vazquez, Miriam Royo and Fernando Albericio
Affiliation:
Keywords: amino acid, combinatorial chemistry, cyclization, libraries, solid support
Abstract: Solid-phase methods for the preparation of hydantoins are reviewed. Furthermore, an optimized method based on the concourse of 1,1-carbonyldiimidazole allows the preparation of hydantoins without loss of chiral integrity.
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Cite this article as:
Vazquez Jesus, Royo Miriam and Albericio Fernando, Re-Evaluation of a Solid-Phase Hydantoin Synthesis, Letters in Organic Chemistry 2004; 1 (3) . https://dx.doi.org/10.2174/1570178043400992
DOI https://dx.doi.org/10.2174/1570178043400992 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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