Synthetic Approaches to the 2004 New Drugs

Jin      Li; Kevin   K.-C.   Liu; Subas      Sakya

doi:10.2174/138955705774933329

Abstract

New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. In addition, these new chemical entities (NCEs) not only provide insights into molecular recognition, but also serve as leads for designing future drugs. To this end, this review covers the syntheses of 12 NCEs marketed in 2004.

Keywords: Synthesis, New Drug, New Chemical Entities

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Mini-Reviews in Medicinal Chemistry

Title: Synthetic Approaches to the 2004 New Drugs

Volume: 5 Issue: 12

Author(s): Jin Li, Kevin K.-C. Liu and Subas Sakya

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Keywords: Synthesis, New Drug, New Chemical Entities

Abstract: New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. In addition, these new chemical entities (NCEs) not only provide insights into molecular recognition, but also serve as leads for designing future drugs. To this end, this review covers the syntheses of 12 NCEs marketed in 2004.

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Li Jin, Liu K.-C. Kevin and Sakya Subas, Synthetic Approaches to the 2004 New Drugs, Mini-Reviews in Medicinal Chemistry 2005; 5 (12) . https://dx.doi.org/10.2174/138955705774933329