Abstract
Although lumbar puncture is generally safe, bleeding into the cerebrospinal fluid (CSF), may occur as a result of trauma during the procedure. As a consequence bacteria (in patients with sepsis) or leukemic cells (in patients with leukemia) circulating in blood may be introduced into the CSF as a result of TLP. Therefore paediatric preventive measures must be taken when performing diagnostic LP procedures in pediatric patients suspected of having leukaemia or bacteremia, including the use of deep sedation or general anaesthesia, collection of the initial diagnostic CSF by a very skilled practitioner, and platelets transfusion for ALL patients with thrombocytopenia and circulating leukaemic cells.
Keywords: Pediatrics, traumatic lumbar puncture, meningitis
Current Pediatric Reviews
Title: The Influence of Traumatic Lumbar Puncture (TLP) on Outcome of Pediatric Patients
Volume: 1 Issue: 3
Author(s): Angela Rech and Algemir L. Brunetto
Affiliation:
Keywords: Pediatrics, traumatic lumbar puncture, meningitis
Abstract: Although lumbar puncture is generally safe, bleeding into the cerebrospinal fluid (CSF), may occur as a result of trauma during the procedure. As a consequence bacteria (in patients with sepsis) or leukemic cells (in patients with leukemia) circulating in blood may be introduced into the CSF as a result of TLP. Therefore paediatric preventive measures must be taken when performing diagnostic LP procedures in pediatric patients suspected of having leukaemia or bacteremia, including the use of deep sedation or general anaesthesia, collection of the initial diagnostic CSF by a very skilled practitioner, and platelets transfusion for ALL patients with thrombocytopenia and circulating leukaemic cells.
Export Options
About this article
Cite this article as:
Rech Angela and Brunetto L. Algemir, The Influence of Traumatic Lumbar Puncture (TLP) on Outcome of Pediatric Patients, Current Pediatric Reviews 2005; 1 (3) . https://dx.doi.org/10.2174/157339605774574944
DOI https://dx.doi.org/10.2174/157339605774574944 |
Print ISSN 1573-3963 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6336 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Domperidone and Long QT Syndrome
Current Drug Safety Novel and Emerging Drugs for Acute Lymphoblastic Leukemia
Current Cancer Drug Targets Aberrant Regulation of Translation Initiation in Tumorigenesis
Current Molecular Medicine Intracellular Trafficking of Plasmids for Gene Therapy: Mechanisms of Cytoplasmic Movement and Nuclear Import
Current Gene Therapy Designing Multiple Ligands – Medicinal Chemistry Strategies and Challenges
Current Pharmaceutical Design ROCK Inhibitors as Emerging Therapeutic Candidates for Sarcomas
Current Cancer Drug Targets Prodrugs and Endogenous Transporters: Are They Suitable Tools for Drug Targeting into the Central Nervous System?
Current Pharmaceutical Design Chemokine Receptors as Targets for Cancer Therapy
Current Pharmaceutical Design Selective Chemokine Receptor-Targeted Depletion of Pathological Cells as A Therapeutic Strategy for Inflammatory, Allergic and Autoimmune Diseases
Recent Patents on Inflammation & Allergy Drug Discovery Signal transduction in Acute Myeloid Leukemia – Implications for Novel Therapeutic Concepts.
Current Cancer Drug Targets The Tumor Stroma as Mediator of Drug Resistance - A Potential Target to Improve Cancer Therapy?
Current Pharmaceutical Biotechnology Spirocyclic Nucleosides in Medicinal Chemistry: An Overview
Mini-Reviews in Medicinal Chemistry Real-Time PCR: Revolutionizing Detection and Expression Analysis of Genes
Current Genomics Cell Proliferation and Cytotoxicity Assays
Current Pharmaceutical Biotechnology T Cell Polarization and the Formation of Immunological Synapses: From Antigen Recognition to Virus Spread
Current Immunology Reviews (Discontinued) Transdermal Penetration of Cytarabine and Its 5-O Alkyl Ester Derivatives
Medicinal Chemistry Clinical Trials of Targeted Alpha Therapy for Cancer
Reviews on Recent Clinical Trials Electrochemical Study of Ellipticine Interaction with Single and Double Stranded Oligonucleotides
Anti-Cancer Agents in Medicinal Chemistry New Tubulin Polymerization Inhibitor Derived from Thalidomide: Implications for Anti-Myeloma Therapy
Current Medicinal Chemistry Protein Microarrays: Technological Aspects, Applications and Intellectual Property
Recent Patents on Biotechnology