A Simple Asymmetric Synthesis of 4-Substituted-2-Oxazolidinones

V.   J.   Sattigeri; A.   S.S.V.   Srinivas; A.      Soni; J.   M.   Khanna; A.      Mehta

doi:10.2174/157017805774296876

Abstract

A novel and efficient synthesis of 4-substituted 2-oxazolidinones is described; the synthesis utilizes Sharpless asymmetric dihydroxylation (AD) of appropriately substituted O-allylcarbamates and intramolecular cyclisation as key steps.

Keywords: chiral, substituted -oxazolidinones, asymmetric dihydroxylation, intramolecular cyclisation

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Letters in Organic Chemistry

Title: A Simple Asymmetric Synthesis of 4-Substituted-2-Oxazolidinones

Volume: 2 Issue: 7

Author(s): V. J. Sattigeri, A. S.S.V. Srinivas, A. Soni, J. M. Khanna and A. Mehta

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Keywords: chiral, substituted -oxazolidinones, asymmetric dihydroxylation, intramolecular cyclisation

Abstract: A novel and efficient synthesis of 4-substituted 2-oxazolidinones is described; the synthesis utilizes Sharpless asymmetric dihydroxylation (AD) of appropriately substituted O-allylcarbamates and intramolecular cyclisation as key steps.

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Sattigeri J. V., Srinivas S.S.V. A., Soni A., Khanna M. J. and Mehta A., A Simple Asymmetric Synthesis of 4-Substituted-2-Oxazolidinones, Letters in Organic Chemistry 2005; 2 (7) . https://dx.doi.org/10.2174/157017805774296876