Focus on Recent Approaches for the Development of New NO-Donors

A.      Gasco; R.      Fruttero; B.      Rolando

doi:10.2174/1389557053402684

Abstract

Recent research developments in the field of NO-donor compounds have concerned conjugation of NO-donor moieties with antioxidant groups, NO-donor targeting, design of NO-donor hybrid drugs and of NOdelivery systems. These new approaches are illustrated and discussed through selected examples.

Keywords: nitric oxide, no-donors, no-donor antioxidants, no-donor targeting, drug/no-donor hybrids, no-delivery systems

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Mini-Reviews in Medicinal Chemistry

Title: Focus on Recent Approaches for the Development of New NO-Donors

Volume: 5 Issue: 2

Author(s): A. Gasco, R. Fruttero and B. Rolando

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Keywords: nitric oxide, no-donors, no-donor antioxidants, no-donor targeting, drug/no-donor hybrids, no-delivery systems

Abstract: Recent research developments in the field of NO-donor compounds have concerned conjugation of NO-donor moieties with antioxidant groups, NO-donor targeting, design of NO-donor hybrid drugs and of NOdelivery systems. These new approaches are illustrated and discussed through selected examples.

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Gasco A., Fruttero R. and Rolando B., Focus on Recent Approaches for the Development of New NO-Donors, Mini-Reviews in Medicinal Chemistry 2005; 5 (2) . https://dx.doi.org/10.2174/1389557053402684