Symptom and Structure Modifying Properties of Chondroitin Sulfate in Osteoarthritis

Jean-Yves      Reginster; Florence      Heraud; Brigitte      Zegels; Olivier      Bruyere

doi:10.2174/138955707782110088

Abstract

Chondroitin sulfate (CS) is a complex carbohydrate polymer with variable sulfation which impacts function. CS exhibits a wide range of biological activities. Many experimental and clinical data are available, affirming that CS represents an effective and safe symptomatic treatment of osteoarthritis (OA) with delayed and sustained effects.

Keywords: Chondroitin sulfate, sulfation patterns, cartilage, glycosaminoglycans, osteoarthritis, SYSADOAs

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Mini-Reviews in Medicinal Chemistry

Title: Symptom and Structure Modifying Properties of Chondroitin Sulfate in Osteoarthritis

Volume: 7 Issue: 10

Author(s): Jean-Yves Reginster, Florence Heraud, Brigitte Zegels and Olivier Bruyere

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Keywords: Chondroitin sulfate, sulfation patterns, cartilage, glycosaminoglycans, osteoarthritis, SYSADOAs

Abstract: Chondroitin sulfate (CS) is a complex carbohydrate polymer with variable sulfation which impacts function. CS exhibits a wide range of biological activities. Many experimental and clinical data are available, affirming that CS represents an effective and safe symptomatic treatment of osteoarthritis (OA) with delayed and sustained effects.

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Reginster Jean-Yves, Heraud Florence, Zegels Brigitte and Bruyere Olivier, Symptom and Structure Modifying Properties of Chondroitin Sulfate in Osteoarthritis, Mini-Reviews in Medicinal Chemistry 2007; 7 (10) . https://dx.doi.org/10.2174/138955707782110088