The Blomia tropicalis Allergens

Kaw      Yan Chua; Nge      Cheong; I-Chun      Kuo; Bee      Wah Lee; Fong      Cheng Yi; Chiung-Hui      Huang; Lip      Nyin Liew

doi:10.2174/092986607780363862

Abstract

Blomia tropicalis allergens are the most important mite allergens in tropical regions. Most of them only have 30-40% sequence identity with their Dermatophagoides counterparts and they share low IgE cross reactivity and exhibit different immunobiology. Unlike the pyroglyphid counterparts, Blo t 5 is the major allergen whereas Blo t 1 only has modest allergenicity.

Keywords: Dermatophagoides, cysteine protease, house dust mite allergens, IgE, RACE cDNA amplification

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Protein & Peptide Letters

Title: The Blomia tropicalis Allergens

Volume: 14 Issue: 4

Author(s): Kaw Yan Chua, Nge Cheong, I-Chun Kuo, Bee Wah Lee, Fong Cheng Yi, Chiung-Hui Huang and Lip Nyin Liew

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Keywords: Dermatophagoides, cysteine protease, house dust mite allergens, IgE, RACE cDNA amplification

Abstract: Blomia tropicalis allergens are the most important mite allergens in tropical regions. Most of them only have 30-40% sequence identity with their Dermatophagoides counterparts and they share low IgE cross reactivity and exhibit different immunobiology. Unlike the pyroglyphid counterparts, Blo t 5 is the major allergen whereas Blo t 1 only has modest allergenicity.

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Yan Chua Kaw, Cheong Nge, Kuo I-Chun, Wah Lee Bee, Cheng Yi Fong, Huang Chiung-Hui and Nyin Liew Lip, The Blomia tropicalis Allergens, Protein & Peptide Letters 2007; 14 (4) . https://dx.doi.org/10.2174/092986607780363862