Synthetic Approaches to the 2005 New Drugs

Subas   M.   Sakya; Jin      Li; Kevin   K.-C.   Liu

doi:10.2174/138955707780363800

Abstract

New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. In addition, these new chemical entities (NCEs) not only provide insights into molecular recognition, but also serve as drug-like leads for designing future new drugs. To these ends, this review covers the syntheses of 22 NCEs marketed in 2005.

Keywords: Synthesis, new drug, new chemical entities, medicine, therapeutic agents

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Mini-Reviews in Medicinal Chemistry

Title: Synthetic Approaches to the 2005 New Drugs

Volume: 7 Issue: 4

Author(s): Subas M. Sakya, Jin Li and Kevin K.-C. Liu

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Keywords: Synthesis, new drug, new chemical entities, medicine, therapeutic agents

Abstract: New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. In addition, these new chemical entities (NCEs) not only provide insights into molecular recognition, but also serve as drug-like leads for designing future new drugs. To these ends, this review covers the syntheses of 22 NCEs marketed in 2005.

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Sakya M. Subas, Li Jin and Liu K.-C. Kevin, Synthetic Approaches to the 2005 New Drugs, Mini-Reviews in Medicinal Chemistry 2007; 7 (4) . https://dx.doi.org/10.2174/138955707780363800