A Case of Fatal Community-Acquired Necrotizing Pneumonia Caused by Panton-Valentine Leukocidin Positive Methicillin-Sensitive Staphylococcus Aureus

Title: A Case of Fatal Community-Acquired Necrotizing Pneumonia Caused by Panton-Valentine Leukocidin Positive Methicillin-Sensitive Staphylococcus Aureus

Volume: 3 Issue: 1

Author(s): Narimon Honarpour and Jenny T. Mao

Affiliation:

Keywords: PVL, MSSA, community-acquired necrotizing pneumonia and massive hemoptysis

Abstract: The expression of Panton-Valentine leukocidin (PVL) has been implicated as a virulence factor for communityacquired Staphylococcus aureus pneumonia with most reported cases involving methicillin-resistant strains. Here we describe a case of community-acquired, PVL-positive methicillin-sensitive Staphylococcus aureus (MSSA) sufficiently virulent to cause rapidly progressive necrotizing pneumonia, massive pulmonary hemorrhage, sepsis, and death in a patient without conventional risk factors (diabetes, advanced age). To our knowledge, this is the first case report of a fatal necrotizing pneumonia caused by PVL-positive MSSA in Los Angeles County.

Cite this article as:

Honarpour Narimon and Mao T. Jenny, A Case of Fatal Community-Acquired Necrotizing Pneumonia Caused by Panton-Valentine Leukocidin Positive Methicillin-Sensitive Staphylococcus Aureus, Current Respiratory Medicine Reviews 2007; 3 (1) . https://dx.doi.org/10.2174/157339807779941776