Design and Synthesis of Metal-Free Artificial Ribonucleases

Ludmila   S.   Koroleva; Inna   Yu.   Serpokrylova; Valentin   V.   Vlassov; Vladimir   N.   Silnikov

doi:10.2174/092986607779816177

Abstract

The present review is aimed at giving a general overview of our results in the field of designing and synthesizing simple peptide-like molecules that mimic structural and functional aspects of natural ribonucleases, as well as designing oligonucleotide-based artificial ribonucleases.

Keywords: Artificial ribonucleases, RNases mimics, oligonucleotide conjugates

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Protein & Peptide Letters

Title: Design and Synthesis of Metal-Free Artificial Ribonucleases

Volume: 14 Issue: 2

Author(s): Ludmila S. Koroleva, Inna Yu. Serpokrylova, Valentin V. Vlassov and Vladimir N. Silnikov

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Keywords: Artificial ribonucleases, RNases mimics, oligonucleotide conjugates

Abstract: The present review is aimed at giving a general overview of our results in the field of designing and synthesizing simple peptide-like molecules that mimic structural and functional aspects of natural ribonucleases, as well as designing oligonucleotide-based artificial ribonucleases.

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Koroleva S. Ludmila, Serpokrylova Yu. Inna, Vlassov V. Valentin and Silnikov N. Vladimir, Design and Synthesis of Metal-Free Artificial Ribonucleases, Protein & Peptide Letters 2007; 14 (2) . https://dx.doi.org/10.2174/092986607779816177