Abstract
Recent updates in the field of echocardiography have resulted in improvements in both image quality and techniques allowing echocardiography to maintain its position as the primary non-invasive imaging modality. In particular, the development of new ultrasound contrast agents and imaging techniques have now made possible the assessment of myocardial perfusion. Myocardial contrast echocardiography utilises acoustically active gas filled microspheres (microbubbles), which have rheology similar to that of red blood cells. The detection of myocardial perfusion during echocardiographic examinations permits simultaneous assessment of global and regional myocardial structure, function, and perfusion, enabling the optimal non-invasive assessment of coronary artery disease. Myocardial contrast echocardiography is equally adept in assessing chronic coronary artery disease as well as acute coronary syndromes. Furthermore, its use is not limited solely to diagnostic assessment. Preliminary evidence suggests that targeted microbubbles may be useful in enhancing delivery of genes / drugs and in clot lysis.
Keywords: Myocardial contrast echocardiography, single photon emission computed tomography, acute myocardial infarction, myocardial blood volume, coronary artery disease, microbubbles
Current Vascular Pharmacology
Title: Myocardial Contrast Echocardiography: Role in Clinical Cardiology
Volume: 4 Issue: 3
Author(s): Girish Dwivedi, Sajad Ahmed Hayat, Rajesh Janardhanan and Roxy Senior
Affiliation:
Keywords: Myocardial contrast echocardiography, single photon emission computed tomography, acute myocardial infarction, myocardial blood volume, coronary artery disease, microbubbles
Abstract: Recent updates in the field of echocardiography have resulted in improvements in both image quality and techniques allowing echocardiography to maintain its position as the primary non-invasive imaging modality. In particular, the development of new ultrasound contrast agents and imaging techniques have now made possible the assessment of myocardial perfusion. Myocardial contrast echocardiography utilises acoustically active gas filled microspheres (microbubbles), which have rheology similar to that of red blood cells. The detection of myocardial perfusion during echocardiographic examinations permits simultaneous assessment of global and regional myocardial structure, function, and perfusion, enabling the optimal non-invasive assessment of coronary artery disease. Myocardial contrast echocardiography is equally adept in assessing chronic coronary artery disease as well as acute coronary syndromes. Furthermore, its use is not limited solely to diagnostic assessment. Preliminary evidence suggests that targeted microbubbles may be useful in enhancing delivery of genes / drugs and in clot lysis.
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Cite this article as:
Dwivedi Girish, Ahmed Hayat Sajad, Janardhanan Rajesh and Senior Roxy, Myocardial Contrast Echocardiography: Role in Clinical Cardiology, Current Vascular Pharmacology 2006; 4 (3) . https://dx.doi.org/10.2174/157016106777698423
DOI https://dx.doi.org/10.2174/157016106777698423 |
Print ISSN 1570-1611 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6212 |
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Cardiovascular disease still remains the leading cause of death in Chronic and End Stage Kidney Disease, accounting for more than half of all deaths in dialysis patients. During the past decade, research has been focused on novel therapeutic agents that might delay or even reverse cardiovascular disease and vascular calcification, ...read more
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