HClO4-SiO2 Catalyzed Multicomponent Reactions for the Synthesis of Privileged Heterocyclic Structures

Pintu Kumar      Mandal; Anup Kumar      Misra

doi:10.2174/157017806779116978

Abstract

A series of multicomponent reactions has been carried out using HClO4-SiO2 as a versatile catalyst. A series of medicinally important heterocyclic core structures have been prepared under solvent-free reaction conditions. In all cases, the reaction conditions were very simple and high yielding.

Keywords: Multicomponent reaction, Pechmann reaction, coumarin, Biginelli reaction, hetero-Diels-Alder, Hantzsch reaction, pyranoquinoline

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Letters in Organic Chemistry

Title: HClO4-SiO2 Catalyzed Multicomponent Reactions for the Synthesis of Privileged Heterocyclic Structures

Volume: 3 Issue: 11

Author(s): Pintu Kumar Mandal and Anup Kumar Misra

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Keywords: Multicomponent reaction, Pechmann reaction, coumarin, Biginelli reaction, hetero-Diels-Alder, Hantzsch reaction, pyranoquinoline

Abstract: A series of multicomponent reactions has been carried out using HClO4-SiO2 as a versatile catalyst. A series of medicinally important heterocyclic core structures have been prepared under solvent-free reaction conditions. In all cases, the reaction conditions were very simple and high yielding.

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Mandal Pintu Kumar and Misra Anup Kumar, HClO4-SiO2 Catalyzed Multicomponent Reactions for the Synthesis of Privileged Heterocyclic Structures, Letters in Organic Chemistry 2006; 3 (11) . https://dx.doi.org/10.2174/157017806779116978