Abstract
Tumor Associated Carbohydrate Antigens (TACAs) constitute powerful tools as tumor markers and as targets for anticancer immunotherapy. In this review, methods of production of glycopeptide-based vaccines, as well as results of preclinical and clinical studies in cancer patients are discussed.
Keywords: Glycosylation, cancer, glycosyltransferase, synthesis, vaccine, immunotherapy, carbohydrate
Mini-Reviews in Medicinal Chemistry
Title: Carbohydrate Antigens: Synthesis Aspects and Immunological Applications in Cancer
Volume: 6 Issue: 12
Author(s): Teresa Freire, Sylvie Bay, Sophie Vichier-Guerre, Richard Lo-Man and Claude Leclerc
Affiliation:
Keywords: Glycosylation, cancer, glycosyltransferase, synthesis, vaccine, immunotherapy, carbohydrate
Abstract: Tumor Associated Carbohydrate Antigens (TACAs) constitute powerful tools as tumor markers and as targets for anticancer immunotherapy. In this review, methods of production of glycopeptide-based vaccines, as well as results of preclinical and clinical studies in cancer patients are discussed.
Export Options
About this article
Cite this article as:
Freire Teresa, Bay Sylvie, Vichier-Guerre Sophie, Lo-Man Richard and Leclerc Claude, Carbohydrate Antigens: Synthesis Aspects and Immunological Applications in Cancer, Mini-Reviews in Medicinal Chemistry 2006; 6 (12) . https://dx.doi.org/10.2174/138955706778992996
DOI https://dx.doi.org/10.2174/138955706778992996 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Mapping the High Throughput SEREX Technology Screening for Novel Tumor Antigens
Combinatorial Chemistry & High Throughput Screening Focus on MicroRNAs as Biomarker in Pediatric Diseases
Current Pharmaceutical Design Alzheimer Disease: What Role for Leptin and Insulin?
Central Nervous System Agents in Medicinal Chemistry Fluorine-18 Labeled Amino Acids for Oncologic Imaging with Positron Emission Tomography
Current Topics in Medicinal Chemistry The Problem of Amino Acid Complementarity and Antisense Peptides
Current Protein & Peptide Science Therapeutics Based on microRNA: A New Approach for Liver Cancer
Current Genomics Calpains as a Target for Therapy of Neurodegenerative Diseases: Putative Role of Lithium
Current Drug Metabolism Resveratrol: A New Potential Therapeutic Agent for Melanoma?
Current Medicinal Chemistry The Chemistry of Bioactive Diterpenes
Current Organic Chemistry Vasorelaxation Caused by Cannabinoids: Mechanisms in Different Vascular Beds
Current Vascular Pharmacology Novel Systemic Markers for Patients with Alzheimer Disease? – A Pilot Study
Current Alzheimer Research Synthesis, Crystal Structure, Characterization and DNA Binding Studies of Novel Copper (II) Complex Based on Amino Acid Schiff Base
Current Organic Chemistry Inhibition of Hypusine Biosynthesis in Plasmodium: A Possible, New Strategy in Prevention and Therapy of Malaria
Mini-Reviews in Medicinal Chemistry Autism, Mitochondria and Polybrominated Diphenyl Ether Exposure
CNS & Neurological Disorders - Drug Targets Cyclodepsipeptides - Potential Drugs and Lead Compounds in the Drug Development Process
Current Medicinal Chemistry Interactions Between Cholinergic and Fibroblast Growth Factor Receptors in Brain Trophism and Plasticity
Current Protein & Peptide Science Peptide Receptor Radionuclide Therapy with Somatostatin Analogues in Neuroendocrine Tumors
Anti-Cancer Agents in Medicinal Chemistry Pharmacological Inhibitors of NAD Biosynthesis as Potential An ticancer Agents
Recent Patents on Anti-Cancer Drug Discovery Platelets in Alzheimer’s Disease-Associated Cellular Senescence and Inflammation
Current Pharmaceutical Design Interleukin-15 in Gene Therapy of Cancer
Current Gene Therapy