Interaction Partners of the PDZ Domain of Erbin

Title: Interaction Partners of the PDZ Domain of Erbin

Volume: 13 Issue: 9

Author(s): Angelika Ress and Karin Moelling

Affiliation:

Keywords: Erbin, PDZ domain, ErbB2, APC, c-Rel, HTLV-1 Tax

Abstract: In order to identify proteins that bind to the PDZ domain of Erbin, we tested the C-termini of several proteins in a yeast two-hybrid assay. ErbB2, APC, β-catenin, c-Rel and HTLV-1 Tax were identified as ligands of the PDZ domain of Erbin. The interactions were verified by co-immunoprecipitation experiments. These findings demonstrate the promiscuity of the PDZ domain of Erbin.

Cite this article as:

Ress Angelika and Moelling Karin, Interaction Partners of the PDZ Domain of Erbin, Protein & Peptide Letters 2006; 13 (9) . https://dx.doi.org/10.2174/092986606778256126