Synthesis of 5-Substituted-1,3,4-Oxadiazole-2(3H)-Thiones Under Microwave Irradiation

Wolfgang      Voelter; Awais      Anwar; Muhammad      Ali; Shahnaz      Perveen; Mubeen      Rani; Sohail   A.   Shahzad; Khalid   M.   Khan

doi:10.2174/157017806776114522

Abstract

A variety of 5-substituted-1,3,4-oxadiazole-2(3H)-thiones were prepared using microwave irradiation as energy source under solvent-free conditions. Reaction times were reduced from 5-14 h to 3-7 min affording high yields from corresponding acyl and aroyl hydrazides.

Keywords: microwave-assisted synthesis, 4-oxadiazolethiones, 5-substituted-1,3

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Letters in Organic Chemistry

Title: Synthesis of 5-Substituted-1,3,4-Oxadiazole-2(3H)-Thiones Under Microwave Irradiation

Volume: 3 Issue: 4

Author(s): Wolfgang Voelter, Awais Anwar, Muhammad Ali, Shahnaz Perveen, Mubeen Rani, Sohail A. Shahzad and Khalid M. Khan

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Keywords: microwave-assisted synthesis, 4-oxadiazolethiones, 5-substituted-1,3

Abstract: A variety of 5-substituted-1,3,4-oxadiazole-2(3H)-thiones were prepared using microwave irradiation as energy source under solvent-free conditions. Reaction times were reduced from 5-14 h to 3-7 min affording high yields from corresponding acyl and aroyl hydrazides.

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Voelter Wolfgang, Anwar Awais, Ali Muhammad, Perveen Shahnaz, Rani Mubeen, Shahzad A. Sohail and Khan M. Khalid, Synthesis of 5-Substituted-1,3,4-Oxadiazole-2(3H)-Thiones Under Microwave Irradiation, Letters in Organic Chemistry 2006; 3 (4) . https://dx.doi.org/10.2174/157017806776114522