Clean and Facile Condensations Reaction of Indoles and Carbonyl Compounds Under Solvent-Free Conditions

Shokoufeh      Mehrazma; Najmoddin      Azizi; Mohammad   R.   Saidi

doi:10.2174/157017806775224251

Abstract

A simple, rapid, atom economy and highly efficient green protocol has been developed for the reactions of indole with carbonyl compounds under solvent- free conditions. The attractive features of these procedures are the mild reaction conditions, high conversions, cleaner reaction profiles, inexpensive and environmentally friendly lithium perchlorate and short reaction times.

Keywords: indole, bis indole, carbonyl compounds, lithium perchlorate, atom economy

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Letters in Organic Chemistry

Title: Clean and Facile Condensations Reaction of Indoles and Carbonyl Compounds Under Solvent-Free Conditions

Volume: 3 Issue: 2

Author(s): Shokoufeh Mehrazma, Najmoddin Azizi and Mohammad R. Saidi

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Keywords: indole, bis indole, carbonyl compounds, lithium perchlorate, atom economy

Abstract: A simple, rapid, atom economy and highly efficient green protocol has been developed for the reactions of indole with carbonyl compounds under solvent- free conditions. The attractive features of these procedures are the mild reaction conditions, high conversions, cleaner reaction profiles, inexpensive and environmentally friendly lithium perchlorate and short reaction times.

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Mehrazma Shokoufeh, Azizi Najmoddin and Saidi R. Mohammad, Clean and Facile Condensations Reaction of Indoles and Carbonyl Compounds Under Solvent-Free Conditions, Letters in Organic Chemistry 2006; 3 (2) . https://dx.doi.org/10.2174/157017806775224251