The Therapeutic Potential of Angiotensin-(1-7) as a Novel Renin- Angiotensin System Mediator

Title: The Therapeutic Potential of Angiotensin-(1-7) as a Novel Renin- Angiotensin System Mediator

Volume: 6 Issue: 5

Author(s): Ana C. S. e Silva, Sergio V. B. Pinheiro, Regina M. Pereira, Anderson J. Ferreira and Robson A. S. Santos

Affiliation:

Keywords: Angiotensin-(1-7), Mas receptor, Angiotensin-converting enzyme 2, Angiotensin II, AVE 0991, Angiotensin antagonists, Renin-Angiotensin System

Abstract: In this review, we show Angiotensin-(1-7) as a novel Renin Angiotensin System mediator that antagonizes cardiovascular and proliferative effects of Angiotensin II and exerts complex renal actions. We also speculate the possibility of new drugs for the treatment of cardiovascular, genitourinary and hepatic diseases by interfering with ACE2- Angiotensin-(1-7)-Mas axis.

Cite this article as:

e Silva C. S. Ana, Pinheiro V. B. Sergio, Pereira M. Regina, Ferreira J. Anderson and Santos A. S. Robson, The Therapeutic Potential of Angiotensin-(1-7) as a Novel Renin- Angiotensin System Mediator, Mini-Reviews in Medicinal Chemistry 2006; 6 (5) . https://dx.doi.org/10.2174/138955706776876203