Metal Release from and Sequestration by Metallothioneins Monitored by Electrochemistry and SPR

Title: Metal Release from and Sequestration by Metallothioneins Monitored by Electrochemistry and SPR

Volume: 12 Issue: 5

Author(s): Lin Liu and Jianxiu Wang

Affiliation:

Keywords: Metallothionein, metal release, sequestration, electrochemistry, surface plasmon resonance

Abstract: Due to the high affinity of metallothioneins (MTs) toward various transition metal ions, MTs play an important role in regulation of essential metals, detoxification of heavy metals, and scavenging of free radicals. In this review, we focus on the recent development on the metal release from and sequestration by MTs characterized by electrochemistry and surface plasmon resonance (SPR). The investigation of metal release and coordination processes is of great significance in illustrating the intriguing role of MTs in environmental toxicology.

Cite this article as:

Liu Lin and Wang Jianxiu, Metal Release from and Sequestration by Metallothioneins Monitored by Electrochemistry and SPR, Current Pharmaceutical Biotechnology 2011; 12 (5) . https://dx.doi.org/10.2174/138920111795470886